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Kazuko Koshiba

Faculty
Department of Applied Biosciences
Research Center for Biomedical Engineering
Research Institute of Industrial Technology
PositionProfessor
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Birthday
Last Updated :2019/05/16

Research Activities

Research Areas

  • Biological Science, Developmental biology

Published Papers

  • Cardiac septation in heart development and evolution., Katano W, Moriyama Y, Takeuchi JK, Koshiba-Takeuchi K, Development, growth & differentiation, 61, (1) 114 - 123, 01 , Refereed
  • Important cardiac transcription factor genes are accompanied by bidirectional long non-coding RNAs., Hori Y, Tanimoto Y, Takahashi S, Furukawa T, Koshiba-Takeuchi K, Takeuchi JK, BMC genomics, 19, (1) , 12 , Refereed
  • Significance of whole-genome duplications on the emergence of evolutionary novelties., Moriyama Y, Koshiba-Takeuchi K, Briefings in functional genomics, 17, (5) 329 - 338, 09 , Refereed
  • Whole-Mount and Section In Situ Hybridization in Mouse Embryos for Detecting mRNA Expression and Localization., Koshiba-Takeuchi K, Methods in molecular biology (Clifton, N.J.), 1752, 123 - 131, Refereed
  • [Evolution and development of heart morphology and coronary circulation in vertebrates]., Moriyama Y, Koshiba-Takeuchi K, Nihon rinsho. Japanese journal of clinical medicine, 74 Suppl 4 Pt 1, 35 - 42, 06 , Refereed
  • Expression analysis of Baf60c during heart regeneration in axolotls and neonatal mice., Nakamura R, Koshiba-Takeuchi K, Tsuchiya M, Kojima M, Miyazawa A, Ito K, Ogawa H, Takeuchi JK, Development, growth & differentiation, 58, (4) 367 - 382, 05 , Refereed
  • Combinatorial Functions of Transcription Factors and Epigenetic Factors in Heart Development and Disease, Koshiba-Takeuchi K, Morita Y, Nakamura R, Takeuchi JK, Nakanishi T, Markwald RR, Baldwin HS, Keller BB, Srivastava D, Yamagishi H, Refereed
  • Sall1 transiently marks undifferentiated heart precursors and regulates their fate., Morita Y, Andersen P, Hotta A, Tsukahara Y, Sasagawa N, Hayashida N, Koga C, Nishikawa M, Saga Y, Evans SM, Koshiba-Takeuchi K, Nishinakamura R, Yoshida Y, Kwon C, Takeuchi JK, Journal of molecular and cellular cardiology, 92, 158 - 162, 03 , Refereed
  • Evolution of the fish heart by sub/neofunctionalization of an elastin gene., Moriyama Y, Ito F, Takeda H, Yano T, Okabe M, Kuraku S, Keeley FW, Koshiba-Takeuchi K, Nature communications, 7, 01 , Refereed
  • Transcriptional Dynamics of Immortalized Human Mesenchymal Stem Cells during Transformation., Takeuchi M, Higashino A, Takeuchi K, Hori Y, Koshiba-Takeuchi K, Makino H, Monobe Y, Kishida M, Adachi J, Takeuchi J, Tomonaga T, Umezawa A, Kameoka Y, Akagi K, PloS one, 10, (5) , Refereed
  • Early patterning and specification of cardiac progenitors in gastrulating mesoderm., Devine WP, Wythe JD, George M, Koshiba-Takeuchi K, Bruneau BG, eLife, 3, 10 , Refereed
  • Epigenetic factors and cardiac development., van Weerd JH, Koshiba-Takeuchi K, Kwon C, Takeuchi JK, Cardiovascular research, 91, (2) 203 - 211, 07 , Refereed
  • Reptilian heart development and the molecular basis of cardiac chamber evolution., Koshiba-Takeuchi K, Mori AD, Kaynak BL, Cebra-Thomas J, Sukonnik T, Georges RO, Latham S, Beck L, Henkelman RM, Black BL, Olson EN, Wade J, Takeuchi JK, Nemer M, Gilbert SF, Bruneau BG, Nature, 461, (7260) 95 - 98, 09 , Refereed
  • Tbx5-dependent rheostatic control of cardiac gene expression and morphogenesis., Mori AD, Zhu Y, Vahora I, Nieman B, Koshiba-Takeuchi K, Davidson L, Pizard A, Seidman JG, Seidman CE, Chen XJ, Henkelman RM, Bruneau BG, Developmental biology, 297, (2) 566 - 586, 09 , Refereed
  • Cooperative and antagonistic interactions between Sall4 and Tbx5 pattern the mouse limb and heart., Koshiba-Takeuchi K, Takeuchi JK, Arruda EP, Kathiriya IS, Mo R, Hui CC, Srivastava D, Bruneau BG, Nature genetics, 38, (2) 175 - 183, 02 , Refereed
  • Tbx20 dose-dependently regulates transcription factor networks required for mouse heart and motoneuron development., Takeuchi JK, Mileikovskaia M, Koshiba-Takeuchi K, Heidt AB, Mori AD, Arruda EP, Gertsenstein M, Georges R, Davidson L, Mo R, Hui CC, Henkelman RM, Nemer M, Black BL, Nagy A, Bruneau BG, Development (Cambridge, England), 132, (10) 2463 - 2474, 05 , Refereed
  • Vertebrate crossveinless 2 is secreted and acts as an extracellular modulator of the BMP signaling cascade., Kamimura M, Matsumoto K, Koshiba-Takeuchi K, Ogura T, Developmental dynamics : an official publication of the American Association of Anatomists, 230, (3) 434 - 445, 07 , Refereed
  • HtrA1 serine protease inhibits signaling mediated by Tgfbeta family proteins., Oka C, Tsujimoto R, Kajikawa M, Koshiba-Takeuchi K, Ina J, Yano M, Tsuchiya A, Ueta Y, Soma A, Kanda H, Matsumoto M, Kawaichi M, Development (Cambridge, England), 131, (5) 1041 - 1053, 03 , Refereed
  • Tbx Genes Specify Posterior Digit Identity through Shh and BMP Signaling., Suzuki T, Takeuchi J, Koshiba-Takeuchi K, Ogura T, Developmental cell, 6, (1) 43 - 53, 01 , Refereed
  • Tbx5 specifies the left/right ventricles and ventricular septum position during cardiogenesis., Takeuchi JK, Ohgi M, Koshiba-Takeuchi K, Shiratori H, Sakaki I, Ogura K, Saijoh Y, Ogura T, Development (Cambridge, England), 130, (24) 5953 - 5964, 12 , Refereed
  • Tbx5 and Tbx4 trigger limb initiation through activation of the Wnt/Fgf signaling cascade., Takeuchi JK, Koshiba-Takeuchi K, Suzuki T, Kamimura M, Ogura K, Ogura T, Development (Cambridge, England), 130, (12) 2729 - 2739, 06 , Refereed
  • Unique expression patterns of matrix metalloproteinases in regenerating newt limbs., Kato T, Miyazaki K, Shimizu-Nishikawa K, Koshiba K, Obara M, Mishima HK, Yoshizato K, Developmental dynamics : an official publication of the American Association of Anatomists, 226, (2) 366 - 376, 02 , Refereed

Misc

  • 心臓の発生・再生・創生 I.心臓の発生と進化 心臓の起源 心筋分化と区画化形成, 小柴和子, 生体の科学, 68,   2017 12 15
  • 心臓・冠循環の基礎研究 脊椎動物の心臓形態と冠動脈循環系における発生と進化, 守山裕大, 小柴和子, 日本臨床, 74,   2016 06 20
  • 臨床応用を目指した基礎研究 再生医療を目指した前臨床研究 心機能再生を目指した特定因子による細胞変換技術開発, 森田唯加, 藤川大地, 堀田秋津, 吉田善紀, 小柴和子, 竹内純, 日本臨床, 73,   2015 06 20
  • 進化と発生からみた生命科学 脊椎動物心臓の発生・再生と進化, 伊藤航平, 守山裕大, 竹内純, 小柴和子, 生体の科学, 66, (3) 212 - 216,   2015 06 15
  • 心臓造形生物学:Heartができるメカニズム 心臓の進化と発生, 守山裕大, 小柴和子, 細胞工学, 33, (11) 1157 - 1164,   2014 10 22
  • シーラカンス研究最前線【Part2:形態】シーラカンスと脊椎動物心臓進化, 守山裕大, 竹内純, 小柴和子, 生物の科学 遺伝, 68, (3) 233 - 237,   2014 05 01
  • 形態進化のロジックを辿る―エボデボ研究最前線[動物篇]【Part2:脊椎動物ボディプランのさらなる多様化】脊椎動物の心臓進化―形態と機能の多様性はどのように生み出されたか, 守山裕大, 竹内純, 小柴和子, 生物の科学 遺伝, 67, (2) 197 - 208,   2013 03 01
  • 発生学・再生学シリーズ 心臓発生とその分子メカニズム, 森田唯加, 小柴和子, 竹内純, 血管医学, 13, (3) 291 - 307,   2012 08 31
  • 血管・心筋再生はどこまできたか 8 心臓発生にかかわるクロマチン・ヒストン制御の役割, 塚原由布子, 小柴和子, 竹内純, Heart View, 15, (8) 787 - 795,   2011 08 09
  • I.循環器の生物学 1.心臓発生と心筋分化誘導のマスター因子, 竹内純, 宮川(富田)幸子, 笹岡陽介, 小柴和子, Annual Review 循環器, 2011,   2011 01 25
  • 幹細胞の基礎研究 心筋細胞の誘導と分化―心筋マスター因子は存在するのか, 竹内純, 小柴和子, 医学のあゆみ, 229, (9) 711 - 719,   2009 05 30
  • 発生学から再生医療へ I 発生学の進歩 器官の極性決定とTbx遺伝子, 竹内純, 小柴和子, 小椋利彦, 医学のあゆみ, 199, (13) 876 - 882,   2001 12 29
  • 前後肢の違いと心臓左右心室決定に関わるTbx遺伝子, 竹内純, 小柴和子, 小椋利彦, 遺伝子医学, 5, (1) 130 - 135,   2001 02 10
  • 情報伝達研究の最前線 発生・文化・形態形成に関する情報伝達 前後肢,心臓左右心室決定にかかわるTbx遺伝子, 小柴和子, 竹内純, 小椋利彦, 医学のあゆみ, 194, (5) 325 - 330,   2000 07 29
  • 眼の背腹軸形成と網膜視蓋投射, 小柴和子, 竹内純, 小椋利彦, 脳21, 3, (3) 381 - 384,   2000 07 20
  • 発生・神経研究の最前線2000 左右軸形成,神経幹細胞,器官再生を含む最新トピックス 第1章 体軸形成 1 前後軸に沿ったパターン形成 3 前後肢の違いを決めるTbx遺伝子とidentityの獲得, 竹内純, 小柴和子, 小椋利彦, 実験医学, 18, (9) 1183 - 1193,   2000 05 25
  • Tbx5 related to dorso-ventral axis formation and retina optic tectum projection of an eye., 小柴和子, 竹内純, 小椋利彦, 細胞工学, 19, (3) 364 - 367,   2000 03
  • In vivo application of the electroporation method. 4. Elucidation of the molecular mechanism of limb bud morphogenesis by the virus gene introduction., 竹内純, 高橋源尚, 小柴和子, 小椋利彦, 細胞工学, 18, (11) 1686 - 1695,   1999 10 22
  • Making a hand or foot? / Tbx5 and Tbx4 determine of fore/hind limb identity., 竹内純, 小柴和子, 小椋利彦, 実験医学, 17, (10) 1241 - 1245,   1999 07 01
  • Tbx5/Tbx4 determines the difference of posterior and anterior limbs., 竹内純, 小柴和子, 小椋利彦, 細胞工学, 18, (6) 779 - 781,   1999 06 01
  • Knockout Mouse Data Book. Shh(Sonic hedgehog), Dhh(Desert hedgehog)., 小柴和子, 野地澄晴, Mol Med, 34, (Dec) 458 - 459,   1997
  • Knockout Mouse Data Book. FGFR-1, FGFR-3., 小柴和子, 野地澄晴, Mol Med, 34, (Dec) 173 - 174,   1997
  • Knockout Mouse Data Book. FGF-3,4,5,7., 小柴和子, 野地澄晴, Mol Med, 34, (Dec) 172 - 173,   1997
  • Knockout Mouse Data Book. BMPR-IA(bone morphogenetic protein receptor-IA)., 小柴和子, 野地澄晴, Mol Med, 34,   1997
  • Knockout Mouse Data Book. BMP-1(bone morphogenetic protein 1)., 小柴和子, 野地澄晴, Mol Med, 34, (Dec) 50 - 51,   1997
  • Knockout Mouse Data Book. BMP-2,4,7, GDF-8,9., 小柴和子, 野地澄晴, Mol Med, 34, (Dec) 51 - 53,   1997