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Nobuyo Tsunoda

Faculty
Department of Nutritional Sciences
Course of Food and Nutritional Sciences
PositionProfessor
Mailtsunoda001[at]toyo.jp In case of sending E-mail, please alternate [at] to @
HomepageURL
Birthday
Last Updated :2019/05/16

Researcher Profile and Settings

Association Memberships

  • JAPANESE SOCIETY OF CLINICAL SPORTS MEDICINE
  • JAPAN SOCIETY FOR LIPID NUTRITION
  • JAPANESE SOCIETY FOR PARENTERAL & ENTERAL NUTRITION
  • JAPAN SOCIETY OF NUTRITION AND FOOD SCIENCE
  • THE JAPANESE SOCIETY OF NUTRITION AND DIETETICS
  • JAPAN SOCIETY OF METABOLISM AND CLINICAL NUTRITION
  • JAPAN SOCIETY FOR THE STUDY OF OBESITY
  • THE JAPAN DIABETES SOCIETY

Research Activities

Research Areas

  • Health/Sports science, Applied health science

Research Interests

    DPP4

Published Papers

  • Vegetable dishes, dairy products and fruits are key items mediating adequate dietary intake for Japanese adults with spinal cord injury, Tsunoda N, Inayama T, Hata K, Oka J, Spinal cord, 05 , Refereed
  • Key Dietary Behavioral and Environmental Factors Mediating Dietary Variety Among Japanese Adults with Spinal Cord Injury, Nobuyo Tsunoda, Takayo Inayama, Kikuko Hata, Jun Oka, International Journal of Nutrition and Food Sciences, 4, (1) 111 - 117, Refereed
  • Associations between abdominal visceral fat and surrogate measures of obesity in Japanese men with spinal cord injury, Takayo Inayama, Yukiharu Higuchi, Nobuyo Tsunoda, Hisako Uchiyama, and Hajimu Sakuma, Spinal Coad, 52 , (11) 836 - 841, Refereed
  • Effects of a comprehensive intervention program, including hot bathing, on physical function in community-dwelling healthy older adults: a pilot randomized controlled trial., Sakurai R, Yasunaga M, Saito K, Fukaya T, Kim MJ, Tsunoda N, Muraki E, Suzuki H, Shinkai S, Watanabe S, Fujiwara Y, Aging clinical and experimental research, 25, (4) 453 - 461, 08 , Refereed
  • Effects of a comprehensive intervention program, including hot bathing, on overweight adults: a randomized controlled trial., Sakurai R, Fujiwara Y, Saito K, Fukaya T, Kim MJ, Yasunaga M, Kim H, Ogawa K, Tanaka C, Tsunoda N, Muraki E, Suzuki K, Shinkai S, Watanabe S, Geriatrics & gerontology international, 13, (3) 638 - 645, 07 , Refereed
  • Evaluation of the Different Methods for Calculation of the Estimated Energy Requirement for Community-Dwelling Individuals with Spinal Cord Injury, INAYAMA TAKAYO, YOKOSE YUKIE, TSUNODA NOBUYO, UCHIYAMA HISAKO, SAKUMA HAJIMU, HIGUCHI YUKIHARU, OKA JUN, KASONO KEIZO, 栄養学雑誌, 榮養學雑誌, 71, (2) 59 - 66, 04 01
  • Dietary Characteristics of Community-dwelling Individuals with Spinal Cord Injuries: Differences by Gender, Age, and Injury Level, HATA KIKUKO, TSUNODA NOBUYO, INAYAMA TAKAYO, 栄養学雑誌, 榮養學雑誌, 70, (6) 346 - 361, 12 01
  • Fenugreek with reduced bitterness prevents diet-induced metabolic disorders in rats., Muraki E, Chiba H, Taketani K, Hoshino S, Tsuge N, Tsunoda N, Kasono K, Lipids in health and disease, 11, 05 , Refereed
  • Improvement in the high-fat diet-induced dyslipidemia and adiponectin levels by fish oil feeding combined with food restriction in obese KKAy mice., Wakutsu M, Tsunoda N, Mochi Y, Numajiri M, Shiba S, Muraki E, Kasono K, Bioscience, biotechnology, and biochemistry, 76, (5) 1011 - 1014, Refereed
  • Dose-dependent effects, safety and tolerability of fenugreek in diet-induced metabolic disorders in rats., Muraki E, Hayashi Y, Chiba H, Tsunoda N, Kasono K, Lipids in health and disease, 10, 12 , Refereed
  • 手首の3軸加速度・3軸角速度を用いた健常者の車椅子走行時における活動量評価のための予備的検討, KIUCHI KAHORI, INAYAMA TAKAYO, ODA HIROYUKI, TSUNODA NOBUYO, OKA JUN, HIGUCHI YUKIHARU, SAKUMA HAJIMU, IKEMOTO SHINJI, 日本臨床スポーツ医学会誌, 日本臨床スポーツ医学会誌 = The journal of Japanese Society of Clinical Sports Medicine, 19, (2) 265 - 271, 04 30
  • Fenugreek Attenuates Lipid Accumulation in Normal Rats, MURAKI ETSUKO, MATSUOKA CHISATO, OIKAWA RINA, SATO SHINOBU, CHIBA HIROSHIGE, TSUNODA NOBUYO, KASONO KEIZO, 日本栄養・食糧学会誌, 日本栄養・食糧学会誌 : Nippon eiy◆U014D◆ shokury◆U014D◆ gakkaishi = Journal of Japanese Society of Nutrition and Food Science, 64, (2) 99-106 (J-STAGE) - 106, 04 10
  • TRPV1 agonist monoacylglycerol increases UCP1 content in brown adipose tissue and suppresses accumulation of visceral fat in mice fed a high-fat and high-sucrose diet., Iwasaki Y, Tamura Y, Inayoshi K, Narukawa M, Kobata K, Chiba H, Muraki E, Tsunoda N, Watanabe T, Bioscience, biotechnology, and biochemistry, 75, (5) 904 - 909, Refereed
  • Regulation of lipid metabolism by palmitoleate and eicosapentaenoic acid (EPA) in mice fed a high-fat diet., Shiba S, Tsunoda N, Wakutsu M, Muraki E, Sonoda M, Tam PS, Fujiwara Y, Ikemoto S, Kasono K, Bioscience, biotechnology, and biochemistry, 75, (12) 2401 - 2403, Refereed
  • Unsaturated fatty acids in fish oil play a role in adequate fat distribution to plasma, liver and white adipose tissue, Shiba S, Tsunoda N, Ito K, Wakutsu M, Muraki E, Sonoda M, Tam PS, Fujiwara Y, Ikemoto S, Kasono K, J. Health Sci, 57, (4) 341 - 349, Refereed
  • 温泉利用が健康増進に与える効果および安全性に関する研究 第1章 温泉利用型複合健康増進プログラムの開発と評価 4節 すぷりんぐ栄養介入プログラム概要, KAKUTA NOBUYO, MURAKI ETSUKO, SAITO KYOKO, 温泉利用が健康増進に与える効果および安全性に関する研究 平成22年度 総括・分担研究報告書, 39 - 44
  • 温泉利用が健康増進に与える効果および安全性に関する研究 第1章 温泉利用型複合健康増進プログラムの開発と評価 1節 生活習慣病予防型プログラム(スリムアップ教室)の介入効果の検証, SAITO KYOKO, FUKAYA TARO, NISHIKAWA TAKESHI, KAKUTA NOBUYO, MURAKI ETSUKO, HAGURA HIROKO, SAKURAI RYOTA, KIN BISHI, YASUNAGA MASASHI, NONAKA KUMIKO, OGAWA KISHIKO, KOSA YOKO, OBA HIROMI, SUZUKI HIROYUKI, MURAYAMA YO, TAKEUCHI RUMI, NAGANUMA RYO, TEI KEIGEN, 温泉利用が健康増進に与える効果および安全性に関する研究 平成22年度 総括・分担研究報告書, 11 - 20
  • 温泉利用が健康増進に与える効果および安全性に関する研究 第1章 温泉利用型複合健康増進プログラムの開発と評価 2節 介護予防型プログラム(元気アップ教室)の介入効果の検証, FUJIWARA YOSHINORI, SAKURAI RYOTA, KAKUTA NOBUYO, MURAKI ETSUKO, HAGURA HIROKO, KIN BISHI, YASUNAGA MASASHI, NONAKA KUMIKO, OGAWA KISHIKO, KOSA YOKO, OBA HIROMI, SUZUKI HIROYUKI, MURAYAMA YO, TAKEUCHI RUMI, NAGANUMA RYO, TEI KEIGEN, 温泉利用が健康増進に与える効果および安全性に関する研究 平成22年度 総括・分担研究報告書, 21 - 32
  • 脊髄損傷者の栄養・食事計画における安静時代謝量測定意義の検討, UCHIYAMA HISAKO, TSUNODA NOBUYO, YOKOSE YUKIE, SAKUMA HAJIME, SHIGETA FUMIKO, OKA JUN, INAYAMA TAKAYO, KASONO KEIZO, 日本栄養士会雑誌, 53, (10) 911 - 918, 10 01
  • Peroxisome proliferator-activated receptors (PPARs)-independent functions of fish oil on glucose and lipid metabolism in diet-induced obese mice., Wakutsu M, Tsunoda N, Shiba S, Muraki E, Kasono K, Lipids in health and disease, 9, 09 , Refereed
  • 医療施設におけるEBN・マネジメントの概念に基づく効率的な栄養管理・食事設計, KATO YUTA, EHATA MIDORI, MURAKI ETSUKO, TSUNODA NOBUYO, NAKAJIMA SATOSHI, KASONO KEIZO, 日本臨床栄養学会雑誌, 30, (1) , 09 20
  • Nuclear factor 1 regulates adipose tissue-specific expression in the mouse GLUT4 gene., Miura S, Tsunoda N, Ikeda S, Kai Y, Cooke DW, Lane MD, Ezaki O, Biochemical and biophysical research communications, 325, (3) 812 - 818, 12 , Refereed
  • Regulatory sequence elements of mouse GLUT4 gene expression in adipose tissues., Miura S, Tsunoda N, Ikeda S, Kai Y, Ono M, Maruyama K, Takahashi M, Mochida K, Matsuda J, Lane MD, Ezaki O, Biochemical and biophysical research communications, 312, (2) 277 - 284, 12 , Refereed
  • Absorption in humans of isoflavones from soy and red clover is similar, Tsunoda N, Pomeroy S, Nestel P, J Nutr, 132, (8) 2199 - 2201, Refereed
  • Localization of exercise- and denervation-responsive elements in the mouse GLUT4 gene, Tsunoda N,Maruyama K,Cooke DW,Lane MD,Ezaki O, Biochem Biophys Res Commun, 267, (3) 744 - 751, Refereed
  • Overexpression of GLUT4 in mice causes up-regulation of UCP3 mRNA in skeletal muscle, Tsuboyama-Kasaoka N,Tsunoda N,Maruyama K,Takahashi M,Kim H,Cooke DW,Lane MD, Biochem Biophys Res Commun, 258, (1) 187 - 193, Refereed
  • Up-regulation of uncoupling protein 3 (UCP3) mRNA by exercise training and douwn-regulation of UCP3 by denervation in skeletal muscles, Tsuboyama-Kasaoka N,Tsunoda N,Maruyama K,Takahashi M,Kim H,Ikemoto S,Ezaki O, Biochem Biophys Res Commun, 247, (2) 498 - 503, Refereed
  • High-monounsaturated fat diet-induced obesity and diabetes in C57BL/6J mice, Tsunoda N,Ikemoto S,Takahashi M,Maruyama K,Watanabe H,Goto N,Ezaki O, Metabolism, 47, (6) 724 - 730, Refereed
  • Regulated expression of 5'-deleted mouse GLUT4 minigenes in transgenic mice: effects of exercise training and high-fat diet, Tsunoda N,Cooke DW,Ikemoto S,Maruyama K,Takahashi M,Lane MD, Ezaki O, Biochem Biophys Res Commun, 239, (2) 503 - 509, Refereed
  • Cholate inhibits high-fat diet-induced hyperglycemia and obesity with Acyl-CoA synthetase mRNA decrease, Ikemoto S,Takahashi M,Tsunoda N,Maruyama K,Itakura H,Kawanaka K,Tabata I,Higuchi M,Tange, T,Yamamoto T,Ezaki O, Am J Physiol, 273 , (36) E37 - E45, Refereed
  • High-fat diet-induced hyperglycemia and obesity in mice: differential effects of dietary oils, Ikemoto S,Takahashi M,Tsunoda N,Maruyama K,Itakura H,Ezaki O, Metabolism, 45, (12) 1539 - 1546, Refereed

Conference Activities & Talks

  • 嚥下食料理教室の取り組みと継続に向けた今後の課題の検討, KANEKO YASUHIKO, HAYAKAWA ERIKA, KAKUTA NOBUYO, KOJIMA NORIKO, IMAIZUMI YOSHINORI, WAKAMATSU TOSHITAKA, 日本在宅医学会大会抄録集,   2014
  • 温泉施設を利用した仲間づくりおよび健康増進プログラムの提供が生活習慣病リスク軽減に及ぼす影響, YAMAKAWA YUKO, KAKUTA NOBUYO, MURAKI ETSUKO, SAITO KYOKO, KASONO KEIZO, 栄養学雑誌,   2011 09 08
  • 生活習慣病の予防および治療と食生活の関連性に関する研究, TSUNODA NOBUYO, 栄養学雑誌,   2008 09
  • 栄養療法導入後のメトホルミン投与が肝臓及び脂肪組織に与える影響, SATO SHINOBU, MURAKI ETSUKO, EHATA MIDORI, OTAKE KAZUO, TSUNODA NOBUYO, KOBAYASHI JUN, KASONO KEIZO, 糖尿病,   2008 04 25
  • 医療施設における栄養管理・食事設計の標準化とQuality Controlのためのシステム構築に関する検討, KATO YUTA, EBATA MIDORI, MURAKI ETSUKO, KAKUTA NOBUYO, NAKAJIMA KEI, KAZONO KEIZO, 日本栄養・食糧学会大会講演要旨集,   2008 04 01
  • 脊髄損傷者における腕時計型行動識別計(ViM)を用いた日常の生活活動量の評価の検討, ODA HIROYUKI, IKEMOTO SHINJI, KAKUTA NOBUYO, OKA JUN, SAKUMA HAJIME, HIGUCHI KOJI, KITABATAKE YOSHINORI, EGAWA KEN'ICHI, IKEKAWA SHIGEKI, INAYAMA TAKAYO, 日本栄養・食糧学会大会講演要旨集,   2008 04 01
  • 糖尿病モデルマウスを用いた食事療法に関する研究―食事中脂肪酸比率の相違における検討―, OKAMURA TOMOHIRO, SHIBA SHOKO, MURAKI ETSUKO, KAKUTA NOBUYO, KAZONO KEIZO, 日本栄養・食糧学会大会講演要旨集,   2008 04 01
  • 腕時計型行動識別計(ViM)を用いた日常生活における身体活動量評価の妥当性の検討, TOMIYAMA ERI, INAYAMA TAKAYO, ODA HIROYUKI, KAKUTA NOBUYO, OKA JUN, FUJIWARA YOKO, IKEMOTO SHINJI, 日本栄養・食糧学会大会講演要旨集,   2008 04 01
  • 糖・脂質代謝及びインスリン感受性に影響する魚油成分の検討, SHIBA SHOKO, KAKUTA NOBUYO, SONODA MARIKO, MURAKI ETSUKO, IKEMOTO SHINJI, KAZONO KEIZO, 日本栄養・食糧学会大会講演要旨集,   2008 04 01
  • 桂皮熱水抽出物が脂肪細胞の糖及び糖質代謝に与える影響, CHIN EN, MURAKI ETSUKO, EBATA MIDORI, TSUNODA NOBUYO, KAZONO KEIZO, 日本薬学会年会要旨集,   2008 03 05
  • フェヌグリークシード投与による生活習慣病への影響~有効成分の検索~, MURAKI ETSUKO, YAMAGUCHI EMI, KIDO KANAKO, CHIBA TAISEI, TSUNODA NOBUYO, KASONO KEIZO, 日本香辛料研究会講演要旨集,   2008

Research Grants & Projects

  • The mechanisms of fish oil effects on improvement of glucose and lipid metabolism and fatty liver, Ministry of Education, Culture, Sports, Science and Technology, Grants-in-Aid for Scientific Research(基盤研究(C)), Keizo KASONO, (1)Fish oil suppresses weight gain and fat accumulation in the liver on weight rebound.We investigated the effect of fish oil on weight rebound in KK-Ay mice. The experiments suggest that fish oil suppresses body weight gain and fat accumulation in the liver on the weight rebound phase in mice. Suppression of fat accumulation in the liver is attributed to inhibition of fatty acid synthesis, enhancement of lipolysis and fatty acid oxidation, and normalization of lipoprotein secretion from the liver.(2)Peroxisome proliferator-activated receptors (PPARs)-independent functions of fish oil on glucose and lipid metabolism in diet-induced obese mice.The experiments suggest that fish oil decreases lipid levels in plasma and liver via PPARs (PPAR-α and PPAR-γ)pathway-independent mechanism, and that glucose tolerance is inversely regulated by PPARs antagonists under diets containing different oils.(3)Unsaturated fatty acids in fish oil play a role in adequate fat distribution to plasma, liver and white adipose tissue.We used hydrogenated fish oil, which has saturated fatty acids with the same carbon chain lengths as the unsaturated fatty acids in fish oil, to clarify the functions of these unsaturated fatty acids on the improvements in lipid and glucose metabolism in mice. Our results indicate that unsaturated fatty acids in the FO diet decrease lipid levels in the liver and maintain the balance of lipid levels in plasma, liver and white adipose tissue. In addition, these results also suggest that C16:1 and C18:1 synthesized in the liver and white adipose tissue may improve glucose tolerance and lipid metabolism in the HFO group.(4)Regulation of lipid metabolism by palmitoleate and eicosapentaenoic acid (EPA) in mice fed a high-fat diet.We investigated whether oral administration of palmitoleate improves disorders of lipid and glucose metabolism in mice fed a high-fat diet to clarify the effects of one of the main components of fish oil. This study suggests that orally administered palmitoleate or EPA at relatively low levels improve lipid metabolism impaired with a lard-rich diet. We found that palmitoleate, as a component of fish oil, as well as EPA plays a pivotal role in improving lipid metabolism.