Japan Society for the Promotion of Science:Grants-in-Aid for Scientific Research
Date (from‐to) : 2013/04 -2017/03
Author : Sadamoto Tomoko; NATSUI HIROAKI; SATO KOHEI; OOUE ANNA; Otsuki Aki; YNEYA MARINA
Circulating estrogen is believed to a dilator of cerebral vessels, but impact of female hormones on the cerebrovascular regulation is not fully understood. In young healthy females, the cerebrovascular CO2 reactivity, a potent mediator of cerebral flow regulation during exercise, was measured in the internal carotid artery (ICA) and the vertebral artery (VA) during early follicular, late follicular, and mid luteal phases of menstrual cycle. The CO2 reactivity in females was similar to that observed in males and unchanged across three phases of menstrual cycle in both ICA and VA, suggesting that female hormones are not determining factors for the cerebrovascular CO2 reactivity.