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Hirobumi Yamamoto

Faculty
Department of Applied Biosciences
Research Center for Life and Environmmental Science
Course of Life Sciences
PositionProfessor
Mail
HomepageURL
Birthday
Last Updated :2019/10/04

Researcher Profile and Settings

Degree

  • (BLANK), Kyoto University

Association Memberships

  • JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY

Research Activities

Research Areas

  • Pharmacy, Chemical pharmacy

Published Papers

  • Transcriptome Analysis of Nine Tissues to Discover Genes Involved in the Biosynthesis of Active Ingredients in Sophora flavescens, Rongchun Han, Hiroki Takahashi, Michimi Nakamura, Somnuk Bunsupa, Naoko Yoshimoto, Hirobumi Yamamoto, Hideyuki Suzuki, Daisuke Shibata, Mami Yamazaki, Kazuki Saito, Biological and Pharmeceutical Bulletin, 38, (6) 876 - 883, 06 , Refereed
  • Two B-type ATP-binding cassette (ABC) transporters localize to the plasma membrane in Thalictrum minus, Nobukazu Shitan, Kazuyoshi Terasaka, Hirobumi Yamamoto, Fumihiko Sato, Kazufumi Yazaki, Plant Biotechnology, 32, (4) 243 - 247, Refereed
  • Improvement of EEG Processing Syetem “BBFFT2ANOVA” -To Generate Detailed Graph Data Corresponding to ANOVA Results-, Hirobumi Yamamoto、Takashi Ajiro, Koichiro Shimomura, Kenichi Kamijo, International Journal of Computer Science and Network Security, 11, (10) 29 - 44, 10 30 , Refereed
  • Molecular Characterization of a Membrane-bound Prenyltransferase Specific for Isoflavone from Sophora flavescens., Kanako Sasaki, Yusuke Tsurumaru, Hirobumi Yamamoto, Kazufumi Yazaki, The Journal of Biological Chemistry, 286, (27) 24125 - 24134, 07 08 , Refereed
  • A Method for EEG Fluctuation Processing -Application to Fertilizer Difference Analysis in Vegetable Ingestion-, Takashi Ajiro, Hirobumi Yamamoto, Koichiro Shimomura, Kenichi Kamijo, IJCSNS International Journal of Computer Science and Network Security, 10, (10) 71 - 82, 10 , Refereed
  • Malonylation is a key reaction in the metabolism of xenobiotic phenolic glucosides in Arabidopsis and tobacco, Goro Taguchi, Takahisa Ubukata, Hatsumi Nozue, Yuki Kobayashi, Maki Takahi, Hirobumi Yamamoto, Nobuaki Hayashida, The Plant Journal, 63, (6) 1031 - 1041, 09 , Refereed
  • HCHL expression in hairy roots of Beta vulgaris yields a high accumulation of p-hydroxybenzoic acid (pHBA) glucose ester, and linkage of pHBA into cell walls, Laiq ur Rahman, Hitomi Kouno, Yuya Hashiguchi, Hirobumi Yamamoto, Arjan Narbad, Adrian Parr, Nicholas Walton, Toshihiro Ikenaga, Yoshie Kitamura, Bioresource Technology, 100, (20) 4836 - 4842, 10 , Refereed
  • A Method for Structure Analysis of EEG Data -Application to ANOVA in Vegetable Ingestion-, Takashi Ajiro, Akiko Yamanouchi, Koichiro Shimomura, Hirobumi Yamamoto, Kenichi Kamijo, International Journal of Computer Science and Network Security, 9, (9) 70 - 82, 09 , Refereed
  • Cloning and Characterization of Naringenin 8-Prenyltransferase, a Flavonoid-Specific Prenyltransferase of Sophora flavescens, Kanako Sasaki, Kouji Mito, Kazuaki Ohara, Hirobumi Yamamoto, and Kazufumi Yazaki, Plant Physiology, 146, (3) 1075 - 1084, 03 , Refereed
  • Outlier Rejection in Massive Trace Element Data for Geographical Origin Identification System of Vegetables, Nobuyoshi Sato, Minoru Uehara, Koichiro Shimomura, Hirobumi Yamamoto, Kenichi Kamijo, Journal of Networks, 2, (5) 61 - 68, 09 , Refereed
  • Exogenous plant H6H but not bacterial HCHL gene is expressed in Duboisia leichhardtii hairy roots and affect tropane alkaloid production, Rahnab L.-ur, Kitamura Y., Yamaguchi J., Murai M., Akiyama K., Yamamoto H., Muranaka T., Ikenaga T, Emzyme and Microbial Technology, 39, (6) 1183 - 1189, 10 03 , Refereed
  • A Distributed Geographical Origin Identification System for Agricultural Products by Trace Element Compositions., N. Sato、M. Uehara、J. Tamaoka、K. Shimomura、Hirobumi Yamamoto, K. Kamijo, International J. Computer Science and Network Security, 5, (10) 55 - 63, 10 , Refereed
  • Molecular cloning, characterization, and downregulation of an acyltransferase that catalyzes the malonylation of flavonoid and naphthol glucosides in tobacco cells., G. Taguchi、Y. Shitchi、S. Shirasawa、Hirobumi Yamamoto, N. Hayashida, The Plant Journal, 42, (4) 481 - 491, 05 , Refereed
  • Metabolism of administered (2RS)-naringenin in flavonoid-producing cultured cells of Sophora flavescens., Hirobumi Yamamoto, H. Kuribayashi、Y. Seshima、P. Zhao、I. Kouno、G. Taguchi、K. Shimomura, Plant Biotechnology, 21, (5) 355 - 359, 12 , Refereed
  • Engineering of ubiquinone biosynthesis using the yeast coq2 gene confers oxidative stress tolerance in transgenic tobacco., K. Ohara, Y. Kokado, Hirobumi Yamamoto, F. Sato, K. Yazaki, The Plant Journal, 40, (5) 734 - 743, 12 , Refereed
  • Stimulating the production of homoisoflavonoids in cell suspension cultures of Caesalpinia pulcherrima using cork tissue., P. Zhao、Y. Iwamoto、I. Kouno、Y. Egami, Hirobumi Yamamoto, , Phytochemistry, 65, (17) 2455 - 2461, 09 , Refereed
  • Cloning and characterization of a glucosyltransferase that reacts on 7-hydroxyl group of flavonol and 3-hydroxyl group of coumarin from tobacco cells., G. Taguchi、T. Ubukata、N. Hayashida、Hirobumi Yamamoto, M. Okazaki, Archives of Biochemsitry and Biophysiology, 95 - 102, 12 , Refereed
  • A Field Survey of Glycyrrhiza glabra L. in Sicily and Spain, Natural Medicines, 52, (3) 259 - 264, Refereed
  • Characterization of leachianoneG 2"-dinethy lally transferase, a novel preny side-chein elongation enzyme for the formation of the lavandulyl group of sophoraflavanone G in Sophora flavescens Ait. cell suspension cultures , Plant Physiology, 133, (3) 1306 - 1313
  • Efficient Production and caoture of q-prenylnaaringenin and leachianoneG-biosynthetic intermediates of sophoraflavanoneG-by the addition of cork tissues to cell Suspension Cultures of Sophora foavescens , Phytochemistry, 62, (7) 1093 - 1099
  • Formation of benzoquinol moiety in cornoside by salidraside monooxygenase, a cytochrome P450 onzyme, from Abeliophyllum disticumCell suspension cultures , Planta, 216, (3) 432 - 436
  • Thalictrum cell cultures and ABC-like transporter , Phytochemistry, 62, (3) 483 - 489
  • Secologanin synthase which catalyzes the oxidative cleavage of loganin into secologanin is a cytochrome p-450, Phytochemistry, 53, (1) 7 - 12
  • Geranylhydroquinone 3"-hydroxylase, a cytochrome P-450 monooxygenase from Lithospermum erythrorhizon cell suspension cultures., Planta, 210, (2) 312 - 317
  • Simultaneous analysis of shikimate-derived secondary metabolites in Lithospermum erythrorhizon cell suspension cultures by high-performance liquid chromatography., Journal of Chromatography B : Biomedical Sciences and Applications, 738, (1) 3 - 15
  • Production of caffeic acid oligomers in Lithospermum erythrorhizon cell suspension cultures., Phytochemistry, 53, (6) 651 - 657
  • Phylogenetic relationship of six Glycyrrhiza species based on rbcL sequences and chemical constituents, Biological and Pharmaceutical Bulletin, 23, (5) 602 - 606
  • Flavanone 8-dimethylallyltransferase in Sophora flavescens cell suspension cultures, Phytochemistry, 54, (7) 649 - 655
  • Transformation of loganin and 7-deoxyloganin into secologanin by Lonicera japonica cell suspension cultures, Phytochemistry, 50, (3) 417 - 422
  • Production of Cornoside in Abeliophyllum distichum cell suspension cultures, Phytochemistry, 48, (2) 273 - 277
  • Seasonal variation of Glycyrrhizin and isoliquiritigenin glycosides in the root of Glycyrrhiza glabra L., Hiroaki HAYASHI, Noboru HIRAOKA, Yasumasa IKESHIRO, Hirobumi YAMAMOTO, Takafumi YOSHIKAWA, Biological & Pharmaceutical Bulletin, 21, (9) 987 - 989
  • Dimethylallyl diphosphate : Kaempferol 8-dimethylallyl transferase in Epimedium diphyllum cell suspension cultures., Phyto chemistry, 44, (1) 23 - 28
  • Alkylamides from pericarps of Zanthoxylum bungeanum, Phytochemistry, 46, (6) 1123 - 1126
  • Organ specific localization of flavonoids in Glycyrrhiza glabra L., Plant Science, 116, (2) 233 - 238
  • Flavonoid variation in the leaves of Glycyrrhiza glabra, Phytochemistry, 42, (3) 701 - 704
  • Absorption and increase in the production of prenylated flavanones in Sophora flavescens cell suspension cultures by cork pieces, Phytochemistry, 43, (3) 603 - 608
  • A Survey of Distribution and Characteristics of Glyoyrrhiza glabraL. in Turkey, Natural Medicines, 49, (2) 129 - 132
  • Stimulation of prenylated flavanone production by mannans and acidic polysaccharides in callus cultures of Sophora flavescens, Phytochemistry, 40, (1) 77 - 81
  • Flavonol glycosides production in cell suspension cultures of Vancouveria hexandra, Phytochemistry, 33, (4) 841 - 846
  • Antiviral and antitumour activities of some Western North American plants with surface exudates (1) Inhibitory effects on HIV-1 reverse transcriptase", Shoyakugaku Zasshi, 47, (3) 295 - 300
  • Flavonol glycosides production in callus cultures of Epimedium diphyllum, H. Yamamoto, K. Ieda, S. Tsuchiya, K. Yan, T. Tanaka, M. Iinuma, M. Mizuno, Phytochemistry, 31, (3) 837 - 840, Refereed
  • Localization of prenylated flavonoids in Sophora flavescens var. angustifolia plants, Zeitschrift f(]J1168[)r Naturforschung, 47c,535-539
  • Prenylated flavanone production in callus cultures of Sophora flavescens var. angustifolia, H. Yamamoto, S. Kawai, J. Mayumi, T. Tanaka, M. Iinuma, M. Mizuno, Zeitschrift fuer Naturforschung Teil C, 46, 172 - 176, Refereed
  • A trifolirhizin malonate from Sophora flavescens var. angustifolia and its stability, H. Yamamoto, M. Ichimura, T. Tanaka, M. Iinuma, M. Mizuno, Phytochemistry, 30, (5) 1732 - 1733, Refereed
  • Energy-requiring uptake of protoberberine alkaloids by cultured cells of Thalictrum flavum, H. Yamamoto, M. Suzuki, T. Kitamura, H. Fukui, M. Tabata, Plant Cell Reports, 8, 361 - 364, Refereed
  • Correlation of papain-like enzyme production with laticifer formation in somatic embryos of papaya, H. Yamamoto, M. Tabata, Plant Cell Reports, 8, 251 - 254, Refereed
  • Participation of an active transportsystem in berberine-secreting cultured cells of Thalictrum minus, H. Yamamoto, M. Suzuki, Y. Suga, H. Fukui, M. Tabata, Plant Cell Reports, 6, 356 - 359, Refereed
  • Cytological changes associated with induction of anthraquinone synthesis in photoautotrophic cell suspension cultures of Morinda lucida, H. Yamamoto, M. Tabata, E. Leistner, Plant Cell Reports, 6, 187 - 190, Refereed
  • Cytological changes associated with alkaloid production in cultured cells of Coptis japonica and Thalictrum minus, H. Yamamoto, K. Nakagawa, H. Fukui, M. Tabata, Plant Cell Reports, 5, 65 - 68, Refereed
  • Enzymatic difference between laticifers and cultured cells of papaya, H. Yamamoto, S. Tanaka, H. Fukui, M. Tabata, Plant Cell Reports, 5, 269 - 272, Refereed

Misc

  • Production and secretion of berberine in plant tissue cultures, Tissue Culture, 16,   1990

Books etc

  • Effects of cork tissues on the production of secondary metabolites in various plant cell cultures
    Recent Research Developments in Biotechnology and Bioengineering  1999
  • Epimedium diphyllum Morr. et Decne. (Baika-ikariso) : In Vitro Cultures and the Production of Isoprenylflavonol flavonol Glycosides
    Biotechnology in Agriculture and Forestry 28 (Springer-Verlag)  1994

Conference Activities & Talks

  • Transcriptome analysis of Sophora flavescens to investigate genes involved in the biosynthesis of active ingredients, Han R, Takahashi H, Nakamura M, Bunsupa S, Yoshimoto N, Yamamoto Hirobumi, Suzuki H, Shibata D, Yamazaki M, and Saito K, 9th CSP-JSP-KSP Joint Symposium on Pharmacognosy (Shangai),   2016 05 29
  • Molecular characterization of O -prenyltransferases for aromatics from Angelica keiskei,   2015 08 11
  • Elucidation of the naphthoquinone ring formation mechanism in Lithospermum erythrorhizon cultured cells,   2015 03 28

Patents

  • 特願2005-41585
  • Manufacture of caffeic acid derivatives by cell cultures of Boragenous Plants, JP2000060588A2

Research Grants & Projects

  • Regulation of useful compounds production in plant cell cultures
  • Study of the production of useful compounds by plant tissue cultures