Tosei Takahashi

Researcher Information

Research funding number

• 30289920

J-Global ID

• 200901074295167760

Research Interests

• 公衆栄養   栄養疫学   栄養調査   public health nutrition   nutritional epidemiology   nutrition survey   

Research Areas

• Life sciences / Healthcare management, medical sociology
• Life sciences / Nutrition and health science
• Life sciences / Hygiene and public health (non-laboratory)
• Humanities & social sciences / Home economics, lifestyle science

Published Papers

• High Prevalence of General and Abdominal Obesity and Relationship of Obesity with Diabetes Mellitus in Patients with Psychiatric Disorders

  Asahi K; Imazaki N; Takahashi T; Takeuchi M; Kimura N; Sasaki E; Uchino H; Murasugi K; Hayakawa A; Katagiri S; Ishizuka N; Suzuki Y; Sekiya K; Takahashi M; Sato E; Uehara Y; Ikemoto S; Inoue S

  Journal of diabetes and obesity 1 (2) 2014/12 [Refereed]
  
• 生活習慣病ハイリスク肥満者に対する健康管理指導(生活習慣介入)による体重減少の生活習慣病関連指標の改善効果

  旭 久美子; 高橋 東生; 竹内 真理; 石塚 典子; 鈴木 洋子; 吉村 英悟; 荒井 勝己; 影山 晴秋; 今関 信夫; 佐藤 栄子; 高橋 美砂子; 石井 広二; 木下 伊規子; 橋口 剛夫; 金高 有里; 蕨迫 栄美子; 住野 清一; 池本 真二; 井上 修二

  日本臨床生理学会雑誌 日本臨床生理学会 44 (3) 137 - 147 0286-7052 2014/08
• Relation between body mass index, a marker of body fat accumulation, or upper body obesity and hypertension, dyslipidemia, or diabetes in the survey of inhabitant health check-up in a certain district of S city

  竹内 真理; 高橋 東生; 佐々木 恵理子

  日本体質医学会雑誌 = The Japanese journal of constitutional medicine 日本体質医学会 75 (1) 20 - 36 1347-7137 2013/02
• 外来通院する精神疾患患者における肥満の頻度と、肥満に合併する生活習慣病の有病率

  竹内 真理; 高橋 東生; 佐々木 恵理子; 内野 英幸; 石塚 典子; 旭 久美子; 鈴木 洋子; 吉村 英悟; 上原 誉志夫; 川久保 清; 井上 修二

  日本臨床生理学会雑誌 日本臨床生理学会 42 (4) 185 - 197 0286-7052 2012/08 [Refereed]
  
• Masked function of amino acid sensors on pancreatic hormone secretion in ventromedial hypothalamic (VMH) lesioned rats with marked hyperinsulinemia

  Noriko Ishizuka; Katsuaki Tanaka; Yoko Suzuki; Yuri Kintaka; Ikiko Kinoshita; Takeo Hashiguchi; Hiroyuki Shimizu; Akira Senoo; Nobuo Imazeki; Yoko Kobayashi; Katsumi Arai; Ryota Haba; Tosei Takahashi; Kahoru Sasaki; Masako Kako; Kaori Hayashi; Toshimasa Osaka; Yuichi Suzuki; Shuji Inoue

  OBESITY RESEARCH & CLINICAL PRACTICE ELSEVIER SCI LTD 6 (3) E225 - E232 1871-403X 2012/07 [Refereed]
  
• Cell proliferation in ventromedial hypothalamic lesioned rats inhibits acute gastric mucosal lesions

  Noriko Ishizuka; Nobuo Imazeki; Akira Senoo; Junko Sakurai; Masaru Sonoda; Masao Kanazawa; Yoko Suzuki; Yoko Kobayashi; Tosei Takahashi; Ryota Haba; Katsumi Arai; Hiroyuki Shimizu; Kahoru Sasaki; Masako Kako; Kaori Hayashi; Yuichi Suzuki; Shuji Inoue

  OBESITY RESEARCH & CLINICAL PRACTICE ELSEVIER SCI LTD 6 (3) E233 - E240 1871-403X 2012/07 [Refereed]
  
• Ventromedial hypothalamic lesions enhance small intestinal cell proliferation in mice

  Noriko Ishizuka; Akira Senoo; Kaori Hayashi; Kahoru Sasaki; Masako Kako; Yoko Suzuki; Nobuo Imazeki; Hiroyuki Shimizu; Yoko Kobayashi; Ryota Haba; Tosei Takahashi; Katsumi Arai; Toshimasa Osaka; Yuri Kintaka; Yuichi Suzuki; Shuji Inoue

  OBESITY RESEARCH & CLINICAL PRACTICE ELSEVIER SCI LTD 6 (3) E241 - E247 1871-403X 2012/07 [Refereed]
  
• Enhanced exercise-induced muscle damage and muscle protein degradation in streptozotocin-induced type 2 diabetic rats

  Hirohide Yokokawa; Ikiko Kinoshita; Takeo Hashiguchi; Masako Kako; Kahoru Sasaki; Akira Tamura; Yuri Kintaka; Yoko Suzuki; Noriko Ishizuka; Katsumi Arai; Yoshiko Kasahara; Mikiko Kishi; Yoko Kobayashi; Tosei Takahashi; Hiroyuki Shimizu; Shuji Inoue

  JOURNAL OF DIABETES INVESTIGATION WILEY-BLACKWELL 2 (6) 423 - 428 2040-1116 2011/12 [Refereed]
  
• 特定保健用食品の再評価と「新規-特定保健用食品」のあり方について

  田中 平三; 高橋 東生; 原島 恵美子

  ニューフードインダストリー 食品資材研究会 53 (9) 1 - 14 0547-0277 2011/09
• Cell proliferation in visceral organs induced by ventromedial hypothalamic (VMH) lesions: Development of electrical VMH lesions in mice and resulting pathophysiological profiles

  Yoko Suzuki; Shuji Inoue; Hiroyuki Shimizu; Noriko Ishizuka; Yoshiko Kasahara; Tosei Takahashi; Katsumi Arai; Yoko Kobayashi; Mikiko Kishi; Nobuo Imazeki; Akira Senoo; Toshimasa Osaka

  ENDOCRINE JOURNAL JAPAN ENDOCRINE SOC 58 (4) 247 - 256 0918-8959 2011/04 [Refereed]
  
• High cardiovascular risk factors among obese children in an urban area of Japan

  Yuki Sato; Emiko Warabisako; Hirohide Yokokawa; Shohei Harada; Masahiko Tsuda; Reiko Horikawa; Yoshihiko Kurokawa; Tomoo Okada; Noriko Ishizuka; Yoko Kobayashi; Mikiko Kishi; Tosei Takahashi; Yoshiko Kasahara; Nobuo Imazeki; Akira Senoo; Shuji Inoue

  OBESITY RESEARCH & CLINICAL PRACTICE ELSEVIER SCI LTD 4 (4) E333 - E337 1871-403X 2010/10 [Refereed]
  
• 肥満者における血中脂肪酸分画の変化に関する検討

  清水 弘行; 岸 美紀子; 石塚 典子; 鈴木 洋子; 小林 葉子; 今関 信夫; 高橋 東生; 瀬野尾 章; 笠原 賀子; 井上 修二

  日本臨床生理学会雑誌 = Japanese journal of applied physiology 日本臨床生理学会 40 (3) 161 - 164 0286-7052 2010/06
• 都市部における小児肥満とそれに伴う生活習慣病の現状

  蕨迫 栄美子; 岡田 知雄; 野口 美奈; 江口 美紀; 津田 正彦; 黒川 叔彦; 佐藤 ゆき; 石塚 典子; 小場 美穂; 丸岡 紀子; 鈴木 洋子; 小林 葉子; 岸 美紀子; 高橋 東生; 笠原 賀子; 井上 修二

  日本臨床生理学会雑誌 = Japanese journal of applied physiology 日本臨床生理学会 40 (1) 27 - 36 0286-7052 2010/02
• Food for children in the Niigata mid prefecture earthquake

  KAWANO Naoko

  Japanese journal of public health 日本公衆衛生学会 56 (7) 463 - 467 0546-1766 2009/07
• A questionnaire study of the local community and the food environment for children in the Niigata mid prefecture earthquake

  KAWANO Naoko

  Japanese journal of public health 日本公衆衛生学会 56 (7) 456 - 462 0546-1766 2009/07
• Impact of the revision of a nutrient database on the validity of a self-administered food frequency questionnaire (FFQ)

  Junko Ishihara; Manami Inoue; Minatsu Kobayashi; Sachiko Tanaka; Seiichiro Yamamoto; Hiroyasu Iso; Shoichiro Tsugane; S. Sasaki; T. Sobue; M. Akabane; M. Iitoi; Y. Iwase; T. Takahashi; K. Hasegawa; T. Kawabata; Y. Tsubono; S. Karita; M. Yamaguchi; Y. Matsumura

  Journal of Epidemiology 16 (3) 107 - 116 0917-5040 2006/05 [Refereed]
  
• ヘルスクレームの科学的根拠(13)健康食品の有効性と疫学の方法

  田中 平三; 高橋 東生

  イルシー 日本国際生命科学協会 (83) 4 - 8 1347-3239 2005
• Food and nutrient intakes assessed with dietary records for the validation study of a self-administered food frequency questionnaire in JPHC Study Cohort I

  S Sasaki; T Takahashi; Y Iitoi; Y Iwase; M Kobayashi; J Ishihara; M Akabane; S Tsugane

  JOURNAL OF EPIDEMIOLOGY JAPAN EPIDEMIOLOGICAL ASSOC 13 (1) S23 - S50 0917-5040 2003/01 [Refereed]
  
• Validity and reproducibility of a self-administered food frequency questionnaire in the JPHC Study Cohort II: Study design, participant profile and results in comparison with Cohort I

  J Ishihara; T Sobue; S Yamamoto; Yoshimi, I; S Sasaki; M Kobayashi; T Takahashi; Y Iitoi; M Akabane; S Tsugane

  JOURNAL OF EPIDEMIOLOGY JAPAN EPIDEMIOLOGICAL ASSOC 13 (1) S134 - S168 0917-5040 2003/01 [Refereed]
  
• Nutritional Survey in School Children Using the 5th Revised Edition Food Composition Tables : Comparactive Analysis by the 5th and 4th Edition

  TAKAHASHI Tosei; YAMANO Yuko; MIYAKAWA Sanpei; KAGAWA Jun

  Journal of Tokyo Women's Medical College 東京女子医科大学 71 (11) 798 - 805 0040-9022 2001/12
• Validity and reproducibility of a self-administered food-frequency questionnaire to assess isoflavone intake in a japanese population in comparison with dietary records and blood and urine isoflavones.

  S Yamamoto; T Sobue; S Sasaki; M Kobayashi; Y Arai; M Uehara; H Adlercreutz; S Watanabe; T Takahashi; Y Iitoi; Y Iwase; M Akabane; S Tsugane

  The Journal of nutrition 131 (10) 2741 - 7 0022-3166 2001/10
• Follow-up studies on life style of school children in terms of privention for adult life style diseases(3)

  TAKAHASHI T

  産業衛生学雑誌 = Journal of occupational health 43 652 - 652 1341-0725 2001/03
• Follow-up studies on life style of school children in terms of privention for adult life style diseases(2)

  MIYAGAWA S

  産業衛生学雑誌 = Journal of occupational health 43 651 - 651 1341-0725 2001/03
• Follow-up studies on life style of school children in terms of privention for adult life style diseases(1)

  YAMANO Y

  産業衛生学雑誌 = Journal of occupational health 43 650 - 650 1341-0725 2001/03
• Pharmacokinetics of soybean isoflavones in plasma, urine and feces of men after ingestion of 60 g baked soybean powder (kinako).

  S Watanabe; M Yamaguchi; T Sobue; T Takahashi; T Miura; Y Arai; W Mazur; K Wähälä; H Adlercreutz

  The Journal of nutrition 128 (10) 1710 - 5 0022-3166 1998/10
• Interpopulation and intrapopulation variability of nutrient intake in five regions of Japan.

  Y Tsubono; M T Fahey; T Takahashi; Y Iwase; Y Iitoi; M Akabane; S Tsugane

  European journal of clinical nutrition 52 (3) 176 - 9 0954-3007 1998/03
• Relationship of Food Intake and Dietary Patterns with Blood Pressure Levels among Middle-Aged Japanese Men

  Yutaka Takashima; Yasuhiko Iwase; Masao Yoshida; Akatsuki Kokaze; Yasushi Takagi; Yoshitaka Tsubono; Shoichiro Tsugane; Tosei Takahashi; Youji Litoi; Masayuki Akabane; Shaw Watanabe; Takashi Akamatsu

  Journal of Epidemiology Japan Epidemiology Association 8 (2) 106 - 115 0917-5040 1998 [Refereed]
  
• Dietary differences with green tea intake among middle-aged Japanese men and women

  Y Tsubono; T Takahashi; Y Iwase; Y Iitoi; M Akabane; S Tsugane

  PREVENTIVE MEDICINE ACADEMIC PRESS INC ELSEVIER SCIENCE 26 (5) 704 - 710 0091-7435 1997/09 [Refereed]
  
• Drink Intake for Female Junior College Students and Their Parents.

  関千代子; 加藤栄子; 岩瀬靖彦; 君羅満; 高橋東生; 飯樋洋二; 赤羽正之

  栄養学雑誌 55 (6) 0021-5147 1997
• Within- and between-person variations in portion sizes of foods consumed by the Japanese population

  Y Tsubono; M Kobayashi; T Takahashi; Y Iwase; Y Iitoi; M Akabane; S Tsugane

  NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL LAWRENCE ERLBAUM ASSOC INC 29 (2) 140 - 145 0163-5581 1997 [Refereed]
  
• Nutrient consumption and gastric cancer mortality in five regions of Japan

  Y Tsubono; T Takahashi; Y Iwase; Y Iitoi; M Akabane; S Tsugane

  NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL LAWRENCE ERLBAUM ASSOC INC 27 (3) 310 - 315 0163-5581 1997 [Refereed]
  
• Phytoestrogens and cancer prevention

  WATANABE Shaw; TAKAHASHI Tosei; ADLERCREUTZ Herman

  環境変異原研究 17 (3) 279 - 283 0910-0865 1996/03
• A data-based approach for designing a semiquantitative food frequency questionnaire for a population-based prospective study in Japan.

  Y Tsubono; S Takamori; M Kobayashi; T Takahashi; Y Iwase; Y Iitoi; M Akabane; M Yamaguchi; S Tsugane

  Journal of epidemiology 6 (1) 45 - 53 0917-5040 1996/03
• Effects of human diets of two different Japanese populations on cancer incidence in rat hepatic drug-metabolizing and antioxidant enzyme systems.

  Y Kanke; Y Iitoi; M Iwasaki; Y Iwase; M Iwama; M Kimira; T Takahashi; S Tsugane; S Watanabe; M Akabane

  Nutrition and cancer 26 (1) 63 - 71 0163-5581 1996
• Oxidative DNA damage induced by silica in vivo.

  Y Yamano; J Kagawa; T Hanaoka; T Takahashi; H Kasai; S Tsugane; S Watanabe

  Environmental research 69 (2) 102 - 7 0013-9351 1995/05
• Oxidative DNA damage in lung tissue of rats exposed to silica dust

  YAMANO Yuko; KAGAWA Jun; HANAOKA Tomoyuki; TAKAHASHI Tousei; ISHIHARA Yoko; KASAI Hiroshi; TSUGANE Shoichiro; WATANABE Shaw

  環境変異原研究 16 (3) 379 - 383 0910-0865 1995/03
• Salty food intake and risk of Helicobacter pylori infection.

  S Tsugane; Y Tei; T Takahashi; S Watanabe; K Sugano

  Japanese journal of cancer research : Gann 85 (5) 474 - 8 0910-5050 1994/05
• Cytochrome P-450 lA1 genotype in lung cancer patients and controls in Rio de Janeiro, Brazil.

  H Sugimura; I Suzuki; G S Hamada; T Iwase; T Takahashi; K Nagura; H Iwata; S Watanabe; I Kino; S Tsugane

  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 3 (2) 145 - 8 1055-9965 1994/03
• Quantitative analysis of 8-hydroxyguanine in peripheral blood cells: an application for asbestosis patients.

  T Hanaoka; S Tsugane; Y Yamano; T Takahashi; H Kasai; Y Natori; S Watanabe

  International archives of occupational and environmental health 65 (1 Suppl) S215-7  0340-0131 1993

MISC

• 学童のスギ花粉症における抗体価と発症への生活習慣の影響

  大久保茂子; 山野優子; 山内武紀; 高橋東生; 宮川三平; 中館俊夫  日本疫学会学術総会講演集(Web)  28th-  126 (WEB ONLY)  2018/02
• Reproducibility and validity of dietary patterns assessed by a food frequency questionnaire used in the 5-year follow-up survey of the japan public health center-based prospective study

  Akiko Nanri; Taichi Shimazu; Junko Ishihara; Ribeka Takachi; Tetsuya Mizoue; Manami Inoue; Shoichiro Tsugane; S. Sasaki; M. Kobayashi; T. Sobue; S. Yamamoto; M. Akabane; Y. Iitoi; Y. Iwase; T. Takahashi; K. Hasegawa; T. Kawabata; Y. Tsubono; H. Iso; S. Karita; M. Yamaguchi; Y. Matsumura  Journal of Epidemiology  22-  205  -215  2012/10
• S市住民健診結果におけるBMIに基づく肥満および上半身肥満の頻度と、高血圧、脂質異常症、糖尿病のリスクとの関連

  竹内 真理; 高橋 東生; 佐々木 恵理子; 内野 英幸; 村杉 謙次; 早川 明子; 木村 典代; 石塚 典子; 上原 誉志夫; 川久保 清; 井上 修二  日本体質医学会雑誌  74-  (2)  97  -98  2012/06
• 外来通院する精神疾患患者における肥満の現状と生活習慣病の有病率

  竹内真理; 竹内真理; 竹内真理; 高橋東生; 佐々木恵理子; 内野英幸; 内野英幸; 石塚典子; 鈴木洋子; 旭久美子; 吉村英悟; 上原誉志夫; 川久保清; 井上修二; 井上修二  日本臨床生理学会雑誌  42-  (5)  2012
• 生活習慣病ハイリスク対象者に対する生活指導介入による生活習慣病関連指標の改善の効果

  旭久美子; 高橋東生; 竹内真理; 石塚典子; 鈴木洋子; 吉村英悟; 井上修二  日本臨床生理学会雑誌  42-  (5)  2012
• S市住民健診結果におけるBMIに基づく肥満および上半身肥満の頻度と,高血圧,脂質異常症,糖尿病のリスクとの関連

  竹内真理; 高橋東生; 佐々木恵理子; 内野英幸; 村杉謙次; 早川明子; 木村典代; 石塚典子; 上原誉志夫; 川久保清; 井上修二  日本体質医学会雑誌  73-  (3)  218  -218  2011/09

Research Grants & Projects

• Evaluation of human diets of two different populations on diseases incidence ; by experimental animal system

  Japan Society for the Promotion of Science：Grants-in-Aid for Scientific Research

  Date (from‐to) : 1997 -1998 

  Author : KANKE 

  To clarify the associations between local dietary habits and disease risks, hepatic enzyme system of drug metabolism and aortic connective tissue component levels were investigated in rats fed the complete human diet consumed in the two Japanese prefectures, Akita (A) and Okinawa (O), where the incidence of cancers was quite different : Okinawa had the lowest and Akita the highest age-adjusted mortality rate. Male Wistar rats were divided into three groups of 10 animals each : the first (control, C) group was fed the MF animal diet (Oriental Yeast, Tokyo, Japan), the second (Akita, A) group the freeze-dried powder from Akita's meals, and the third (Okinawa, O) group the mill of Okinawa's meals. After animals were given the corresponding diets for eight weeks, the final body weight of the O diet group was significantly higher than that of the A diet group, presumably because of the difference in food efficiency. However, there were no changes between two groups in the hepatic drug-metabolizing enzyme system (cytochrome P-450 content and activities of sulfotransferase, UDP-glucuronyltransferase, glutathione S-transferase) and aortic connective tissue component levels (collagen, elastin and cholesterol). Moreover, the CClィイD24ィエD2 treatment changed, regardless of human (A and O) diets, the serum and hepatic enzyme levels.
• 公衆栄養における栄養調査の精度管理

  総合研究
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